COM port not visible

Hi, I am using a Daisy Seed and protoboards to add an SD and MIDI interface. I programmed the Daisy to send messages via COM-port to the PC

Sometimes the COM port is invisible when turning ON the Daisy when it is in the protoboard. This does not happen when the daisy is not connected to anything

I am using this circuit, similar to Daisy Pod

To help me troubleshoot my circuit, why could daisy stop sending COM messages? Shortcircuit?